Week 6 NFL Odds: All 14 Games, Spreads, Totals — SkimNews
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- Week 6 NFL odds are released for all 14 matchups spanning Thursday, Oct. 15 through Monday, Oct. 19, with spreads, moneylines, and totals posted via DraftKings.
- Seattle Seahawks are 2.5-point favorites over the Denver Broncos on Thursday Night Football, with the lowest total on the board at 40.5 points.
- Jacksonville Jaguars are 2.5-point favorites over the Houston Texans in the London game (total 42.5), while the Buffalo Bills are 6-point road favorites against the Las Vegas Raiders.
- Los Angeles Rams are laying the largest spread of the week at -12.5 against the Arizona Cardinals (total 52.5), with the Rams moneyline at -877 reflecting heavy implied probability.
- Kansas City Chiefs are 8.5-point road favorites over the Los Angeles Chargers, and the Green Bay Packers are 1.5-point favorites over the Dallas Cowboys in a pair of marquee Sunday matchups (both totals at 52.5).
- Cleveland Browns vs. Baltimore Ravens features the Ravens as 4.5-point favorites (total 40.5), while the New England Patriots are 7.5-point road favorites at the New York Jets (total 43.5).
- Monday Night Football closes the week with the San Francisco 49ers as 7.5-point favorites over the Washington Commanders (total 50.5).
Why it matters: The Rams-Cardinals 12.5-point spread is the largest of Week 6, signaling oddsmakers expect a blowout — bettors taking Arizona would need a two-touchdown cushion plus the hook to cash. Five games carry totals at 52.5 (Rams-Cardinals, Bills-Raiders, Packers-Cowboys, Falcons-Bears), suggesting bookmakers expect offensive shootouts in those matchups despite a league-wide scoring dip to 23.3 points per game.
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