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Smelling Chocolate Boosts Reps, Cuts Hunger
Men who smelled dark or milk chocolate before and during leg exercises completed more repetitions without feeling increased exertion, with dark chocolate also reducing appetite despite fasting.
FDA Joins UK, EU Push to Phase Out Animal Drug Tests
Regulators in the US, UK, and EU are pushing to replace animal testing with alternatives like organ-on-chip devices, which have outperformed animal models at flagging drug toxicity in clinical trials.
Scientists discover a major brain shift between ages 50 and 75
Brain cells undergo sweeping changes in how their genomes are regulated between ages 50 and 75, according to a new Science study that mapped single-cell gene activity and three-dimensional DNA structu
FDA Opens Pilot to Speed Drug Testing Timelines
The FDA on Tuesday began accepting applications for a pilot program under HHS's Operation TrialBlazer, designed to compress the timeline for drugmakers to begin testing products in humans and keep pac
STAT+: Pharmalittle: We’re reading about a GSK deal for a drug from China, job losses in the U.S., and more
GSK acquired global rights to a preclinical-stage multiple myeloma drug from China's Chimagen Biosciences for up to $750 million, while separately the FDA held a four-hour public meeting to establish
Docs Reveal Medicare AI Prior Auth Pilot Was Rushed, Flawed
Newly obtained documents reveal that Medicare's AI prior authorization pilot was rushed and riddled with problems, according to STAT+ reporting.
LSD could be approved for anxiety in the US in 2027
LSD could win FDA approval for generalized anxiety disorder as soon as 2027, after a Definium Therapeutics trial found a single dose cut anxiety scores by 9.8 points versus 4.7 for placebo, with no se
Vera's Trutakna Posts Strong Phase 3 Results in IgAN
Vera Therapeutics reported final two-year Phase 3 data showing its drug Trutakna stabilized kidney function and cut kidney-related complications in patients with the autoimmune disease IgA nephropathy
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A New Headset to Help With Depression Is Now Available in the US
Flow Neuroscience's at-home brain stimulation headset for depression is now available by prescription in the US, offering an FDA-cleared, nondrug alternative at $2,200 for an initial 10-week course.
Exercise — and echocardiograms — in space protected astronauts’ hearts in study
A Circulation study of 13 astronauts who performed their own echocardiograms during six months in space found that exercise regimens preserved cardiac structure and function, with researchers calling
Slime Mould Grad Student Stars In New Sci-Fi Novel
An author's forthcoming sci-fi novel 'A Wall Is Also a Road' centers on a cellular slime mould graduate student, with its alien biology, setting, and ancient-Roman subplot grounded in consultations wi
One of the fundamental forces is stronger than we thought
Researchers at Johannes Gutenberg University Mainz used lattice quantum chromodynamics to calculate the electroweak force's strength with unprecedented precision, finding it about 1% stronger than pre
Ebola outbreak in DRC has peaked, say authorities, as infection rates slow
DRC Health Minister Samuel Roger Kamba declared the country's 17th Ebola outbreak has peaked, with daily new cases falling from about 120 to 80, though African CDC officials and lawmakers warned again
Nearly 10,000 patients reveal what works best for knee arthritis pain relief
A network meta-analysis of 139 clinical trials covering nearly 10,000 patients found that simple, accessible therapies like knee braces, hydrotherapy, and exercise outperformed high-tech options such
Plague Killed Families 5,500 Years Before Black Death
Ancient DNA from Lake Baikal burial sites shows plague infected 18 of 46 tested hunter-gatherers (~40%) 5,500 years ago — millennia before the Black Death. The prehistoric strains carried a unique sup
Reading for pleasure boosts memory, empathy and mental health
A Cambridge-led review pooling dozens of studies and tens of thousands of participants links reading for pleasure to greater brain grey matter, reduced stress, and a lower risk of cognitive decline in
Kennedy Returns to Keynote Anti-Vaccine Group He Once Led
Health Secretary Robert F. Kennedy Jr. will keynote this week at the Children's Health Defense conference in Washington, his first public embrace of the anti-vaccine organization he founded since taki
Brain Implant Lets Paralyzed Patients Speak and Gesture via Avatar
A brain implant covering the sensorimotor cortex has decoded simultaneous speech and gestures from two paralyzed patients via an avatar, with gestures predicted at 66–88% accuracy.
Trump Sends $500 Checks to ACA Enrollees Before Midterms
President Trump is funneling $500 checks to a specific subgroup of Affordable Care Act enrollees right before the midterms, a move STAT frames as embodying the Republican health policy approach of usi
Novo Nordisk Rebrands to Novo, Targets Eli Lilly
Novo Nordisk is rebranding to "Novo" and overhauling its corporate culture as CEO Mike Doustdar admits the drugmaker must "rethink" strategy to reclaim market share lost to rival Eli Lilly in the obes
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