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Rare Variant Linked to 25x Higher Lung Cancer Odds
Researchers have identified a rare genetic variant associated with 25-fold higher odds of lung cancer in never-smokers, publishing the findings Thursday in the journal Science using genetic data from
Researchers Get Visa Reprieve; Definium Shares Psychedelics Data
STAT's Readout LOUD podcast this week covers a court reprieve for international researchers facing visa uncertainty and Definium's new psychedelics data, examining the implications for U.S. medical re
New hope for breast cancer patients as life-extending drug now on NHS in England
England's NHS will now cover Enhertu for roughly 1,000 HER2-low breast cancer patients annually after NICE reversed its 2024 rejection — a turnaround driven not by lower drug prices but by revised cos
Scientists find a natural gut compound that helps heal the intestine
University of Louisville researchers found that urolithin A, a compound gut bacteria produce from foods like pomegranates and berries, activates a protective AHR-NLRP6 pathway that repairs the intesti
Textbooks may have misdrawn this basic brain structure for 100 years
Johns Hopkins researchers discovered that brain cell axons form pearl-like swellings rather than the smooth tubes depicted in textbooks for a century. Follow-up work has confirmed the same pearled arc
Adar1 Capital Analyst's Pitch Becomes Atopic Dermatitis Biotech
Adar1 Capital analyst Mohit Gupta spent two years turning his pitch into a new company focused on long-acting antibody treatments for atopic dermatitis, marking a departure from the hedge fund's usual
Sellas GPS Trial Delayed a Year, Poised to Fail
STAT columnist Adam Feuerstein predicts Sellas Life Sciences' Phase 3 REGAL trial of immunotherapy galinpepimut-S will fail to extend survival in acute myeloid leukemia patients, citing a nearly year-
Scientists pinpoint when black holes launch jets
Australian and US researchers have identified the exact moment supermassive black holes launch powerful jets after devouring stars, finding they 'burp' at a predictable feeding threshold regardless of
STAT+: The FDA’s rebuilding effort is running into a new challenge
The FDA's push to hire over 2,000 workers and reverse Elon Musk's DOGE-era layoffs has hit bureaucratic delays caused by those very same cuts, creating an ironic bottleneck in the agency's rebuild.
NHS to Cover AstraZeneca's Enhertu After Pricing Deal
England's NHS agreed to cover AstraZeneca's breast cancer drug Enhertu, ending a years-long pricing dispute and extending access to an estimated 1,000 patients, partly thanks to a U.S.-U.K. drug prici
New mesothelioma drug turns cancer’s own defenses against it
University of Vermont researchers helped develop RSO-021, an experimental mesothelioma drug that disables PRX3 — a mitochondrial antioxidant enzyme cancer cells depend on — controlling disease in 67%
Black and green rice contain unique beneficial fats, study finds
Researchers at Hokkaido University identified 196 lipids across 56 japonica rice cultivars and found that black and green varieties contain unique beneficial fats that break down more slowly than whit
Skull Bone Marrow Houses Brain-Fighting Immune Hubs
Washington University researchers discovered lymph node-like immune structures in mouse skull bone marrow that respond to brain tumors faster than distant lymph nodes, and a gel treatment targeting th
House GOP Bill Would Reshape MedPAC's MA Analysis
House Ways and Means Committee Republicans advanced a bill on a party-line vote directing MedPAC to study Medicare Advantage overpayments in a manner more favorable to insurers, bucking recent scrutin
Cassidy Blames Trump Vaccine Policy as Measles Deaths Rise
Senator Bill Cassidy publicly blamed the Trump administration's vaccination policies for a resurgence of US measles deaths, pressing Trump's surgeon general nominee to clearly reject debunked claims l
Tell HN: An inside view of Montana's new biotech law
Montana's new SB535 law lets biotechs with Phase 1-stage drugs charge patients for experimental treatment outside clinical trials under state-licensed oversight, ending the federal rule that bars spon
Study: Women Routinely Get Less Active Treatment Than Men
A University of St Andrews review of 38 global studies found that women with cardiovascular disease, kidney disease, Parkinson's, and other conditions were consistently less likely than men to receive
Asteroid hit the moon and flung rocks 120 kilometres from the crater
Astronomers have watched a massive asteroid impact create a new 222-metre crater on the moon — the largest ever observed forming in real time — and discovered it flung debris more than 120 kilometres
Why Dogs Ignore Low-Flying Planes — Readers Weigh In
Readers respond to the question of why dogs don't look up at low-flying planes, with anecdotes ranging from a thunder-fearing dog that hides, to Labradors that glance briefly, to a collie that activel
Stanford Builds Mice With Half-Human Brains
Stanford researchers have engineered mice whose brains are roughly half human, transplanting lab-grown brain cells into rodents bred without a cortex or hippocampus in order to study disorders like sc
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