2026 Week 1 NFL score predictions, odds, best picks today: Expert reveals exact scores for every NFL game — SkimNews

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- Eric Cohen released exact score predictions for every game on the NFL's 16-game Week 1 slate, finishing the 2025-26 season with a 188-96-1 straight-up record (66%).
- Cohen's top pick is the Texans (+1.5, O/U 44.5) upsetting the Bills 23-20, calling Houston's defense the best in the NFL.
- Houston has won 4 of the last 5 meetings against Buffalo by a single possession, with the Texans scoring 22-23 and Buffalo scoring 19-20 in each of Houston's three wins since 2020.
- Josh Allen has 10 turnovers in over three career road starts compared to just 5 passing touchdowns, and the Texans sacked him 8 times with 2 interceptions in last season's matchup.
- Cohen is also calling for a road team to win by double digits elsewhere on the Week 1 slate, making alternate lines an attractive angle.
- Exact score wagers on the Chiefs vs. Broncos Monday night opener could return anywhere from +6000 to +15000, reflecting the high-risk, high-reward nature of the bet type.
Why it matters: Cohen's 66% straight-up hit rate last season gives his exact-score calls extra credibility for bettors weighing high-payout Week 1 score props. With the Texans catching 1.5 points but Cohen picking them outright at 23-20, his predicted scoring margins line up almost identically with Houston's historical scoring pattern against Buffalo — a matchup-specific edge bettors can quantify against the spread.
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