Texans vs. Colts predictions, NFL picks, start time: Use Polymarket promo code CBSSPORTS for $50 bonus — SkimNews
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- Houston Texans visit Indianapolis as Polymarket favorites ($0.58) over the winless Indianapolis Colts ($0.42) in Sunday's 1 p.m. ET Week 3 matchup at Lucas Oil Stadium
- Polymarket also lists the Texans at $0.52 to win by more than 2.5 points and $0.51 for the combined total to exceed 42.5 points
- C.J. Stroud has thrown for 627 yards (fourth in the NFL) with two touchdowns and no interceptions through two games, while Houston's defense — which led the NFL in total defense last season — has seven sacks in 2026
- Daniel Jones returned from an Achilles injury to throw for 210 yards against Kansas City, while running back Jonathan Taylor has 190 rushing yards and four touchdowns this season
- The Indianapolis Colts defense is allowing a league-worst 514.5 yards per game — nearly 60 more than the 31st-ranked Lions — and will be without receiver Alec Pierce on Sunday
- Houston has won five consecutive meetings against Indianapolis, with an average margin of 4.2 points during that streak
- The SportsLine Projection Model has the Colts winning in 43% of its 10,000 simulations, undercutting the Texans' favorite status on Polymarket
Why it matters: With both clubs at 0-2, the loser drops to 0-3 and faces an uphill AFC South climb before October; the Texans' pass rush (47 sacks in 2025, seven already in 2026) and Stroud's clean start face an Indy unit surrendering a league-worst 514.5 yards per game — a mismatch Polymarket has only half-priced in with a $0.58 favorite tag.
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