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USC: Methionine-Tuned Diet Made Mice Eat More, Lose Fat
USC researchers found that mice fed a modified Mediterranean-style longevity diet ate more food than any other group yet lost body fat and showed longer healthspan, with a human-data analysis of more
Relativity Warps Chemical Bonds in First Observation
Researchers have observed special relativity reshaping chemical bonds for the first time, using a chilled bismuth-carbon molecule whose electrons move at relativistic speeds near the heavy atom's nucl
Donor retinas respond to light 10 hours after death
Researchers in Barcelona kept donated human retinas responding to light for up to 10 hours after death — double the previous record — by perfusing eyes with oxygenated blood, marking a key step toward
Outbreak of diarrhea-causing parasite grows to more than 1,000 cases
Michigan's cyclospora outbreak has grown to 992 confirmed cases—the largest in state history—while neighboring Ohio reports more than 500 cases and 28 other states investigate similar illnesses with n
STAT+: ARPA-H launches $160 million effort to develop custom gene editing drugs
ARPA-H announced Thursday it will spend up to $160 million on THRIVE, a new program backing seven teams developing custom gene editing treatments for rare diseases across multiple organ systems, with
Thermodynamics rebuilt on gauge theory math
A researcher at the London School of Economics is rebuilding the 200-year-old theory of thermodynamics using the mathematics of gauge theory, a framework typically used in quantum field theory, potent
White House Reviews FDA Commissioner Finalists
The White House is narrowing finalists for FDA commissioner as the agency operates under acting leadership since Marty Makary's earlier resignation, while a STAT roundup also flags AstraZeneca and Ion
Injection halves chromosome errors in older eggs
Researchers at Germany's Ovo Labs have developed an mRNA injection that cut premature chromosome separation in older human eggs roughly in half, offering what independent experts call the first therap
A worm that lived half a billion years ago preferred turning right
Fossils of a 555-million-year-old worm from South Australia reveal that the ancient creature had a preference for turning right, potentially the oldest known evidence of handedness and a sign that com
AstraZeneca, Ionis heart drug Wainua fails pivotal trial
AstraZeneca and Ionis Pharmaceuticals' partnered heart drug Wainua failed to outperform placebo in a pivotal ATTR-CM trial, hitting both companies' stocks in premarket trading on Thursday.
Seniors Lead Cannabis Adoption; Doctors Trail Behind
In an opinion piece, Dr. Peter Grinspoon of Massachusetts General Hospital argues that seniors are now the fastest-growing group of medical cannabis patients but most physicians lack the training to c
Obesity Disease Label Serves Drugmakers, Op-Ed Argues
An opinion piece argues that classifying obesity as a disease primarily serves pharmaceutical companies like Eli Lilly and Novo Nordisk, redirecting attention from social and environmental interventio
STAT+: The quest to save Grace — and clear the way for rare disease patients everywhere
Matt Wilsey has spent a decade and $70 million developing a gene therapy for his 15-year-old daughter Grace's ultra-rare NGLY1 deficiency; with 10 patients treated and his company out of cash, he is n
Vitamin A Signals Convert Blue Cones in Fetal Eye
Johns Hopkins researchers found that blue cone cells in the fetal eye convert into red and green cones—rather than migrating outward—under the influence of vitamin A-derived retinoic acid and thyroid
Semaglutide Dosing Errors Fueled Poison Call Spike
Research from the University of Texas at San Antonio links a dramatic surge in U.S. poison control calls about semaglutide (Ozempic and Wegovy) to the drug's 2021 FDA approval for weight management, w
Harvard scientists turn a silicon chip into a DNA writing machine
Harvard researchers have built a silicon chip that simultaneously synthesizes 64 distinct DNA sequences using electricity-triggered enzymatic reactions in water, potentially replacing the hazardous or
Silica nanoparticles cured aggressive prostate cancer in mice
Weill Cornell researchers engineered ultrasmall silica nanoparticles that selectively killed aggressive prostate cancer cells and reactivated the immune system in mice, producing complete remissions w
A country that made huge progress on measles now reports 120,000 cases
Bangladesh is battling a devastating measles outbreak with over 120,000 suspected and confirmed cases and nearly 750 deaths—mostly children—since mid-March, reversing years of progress toward eliminat
Bacterial 'docking domains' unlock cancer drug engineering
University of Warwick researchers have decoded how bacterial enzymes cooperate to produce multiple variants of powerful anti-cancer drugs, identifying molecular 'docking domains' as the connectors beh
RFK Jr. plans Covid vaccine injury list for compensation
Health Secretary Robert F. Kennedy Jr. is preparing a federal list of injuries presumed to be caused by Covid-19 vaccines, creating a new pathway for claimants to seek government compensation.
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